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24 repos for desktop · Any agent · DataClear

Open-source, desktop-grade AI agent that gets real work done — data analysis, slides, docs, video & web research. Built on OpenClaw; runs tools on your real desktop and takes commands from your phone via WeChat, Feishu, DingTalk & Telegram.

6k
deeleeramone/
PyWry
deeleeramone/PyWryFrameworks & SDKs

PyWry is a cross-platform app factory, rendering engine and UI toolkit for Python that produces native desktop, web, and notebook experiences from a single API.

93

5ire is a cross-platform desktop AI assistant, MCP client. It compatible with major service providers, supports local knowledge base and tools via model context protocol servers .

5.3k

Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

1.1k
JamsusMaximus/
trainingpeaks-mcp

TrainingPeaks MCP server for Claude Desktop, Code and Cowork. No API approval needed - works with any account. Query workouts, CTL/ATL/TSB fitness data, power PRs via natural language.

156

Kotlin Multiplatform sample with SwiftUI, Jetpack Compose, Compose for Wear, Compose for Desktop, and Compose for Web clients along with Ktor backend.

3.4k
zenml-io/
mcp-zenml

MCP server to connect an MCP client (Cursor, Claude Desktop etc) with your ZenML MLOps and LLMOps pipelines

49
aloth/
PowerSkills

Windows PowerShell toolkit for AI agents: Microsoft 365 (mail, calendar, Teams, SharePoint, OneDrive) via Work IQ + Microsoft Graph, Outlook COM, Edge browser (CDP), desktop, and system control - all returning structured JSON.

35

Open-source desktop SQL workspace for PostgreSQL, MySQL/MariaDB, SQLite and 15+ more databases like DuckDB, ClickHouse, Redis and Firestore. Built-in MCP server for Claude, Cursor and Devin, SQL notebooks and visual EXPLAIN.

4.9k
sandraschi/
calibremcp

Calibre library automation via FastMCP — metadata, shelves, RAG-friendly export. Companion to Calibre, not a replacement. For Cursor / Claude Desktop.

42
YaoApp/yaoHarnesses

✨ All your agents and workspaces in one place, on every device you own. Track tasks on a board, accessible from desktop, mobile, browser, or API. Self-hosted.

7.9k

Chat2DB is a free, cross-platform, local-first database client and SQL workspace for developers, DBAs, analysts, and data teams. Connect to 40+ databases, manage data, edit and run SQL, and use your own AI model to generate, explain, and optimize queries. Available on desktop, web, Docker, and CLI, with MCP support.

28k
Cicatriiz/
healthcare-mcp-public

A Model Context Protocol (MCP) server providing AI assistants with access to healthcare data and medical information tools, including FDA drug info, PubMed, medRxiv, NCBI Bookshelf, clinical trials, ICD-10, DICOM metadata, and a medical calculator.

127
kevinluosl/
deepbot

DeepBot is a system-level AI assistant built for both personal productivity and enterprise workflows — one-click setup, seamless experience, and native Feishu integration.

2.3k
cafferychen777/
ChatSpatial

MCP server for spatial transcriptomics analysis through natural language interfaces.

44

vMLX - Use MLX models easily - JANGQ (GGUF for MLX) - Not dependant on mlx_vlm

843
atilaahmettaner/
tradingview-mcp

TradingView MCP server — real-time market data, technical analysis, screeners & backtesting for Claude, ChatGPT, Cursor & any MCP client. Stocks, crypto, forex & futures across global exchanges. Hosted or self-host.

4.4k
maxanatsko/
mcp-engine-public

The SemanticOps MCP (formerly MCP Engine) is a Power BI tool that lets AI assistants like Claude interact with your Power BI models programmatically: read your model structure, run DAX queries, modify your semantic model, and perform advanced analytics - all through natural conversation.

256

Ontology-based MCP server that analyzes database schemas (PostgreSQL, Snowflake, ClickHouse, Dremio) and generates RDF/OWL ontologies with SQL mappings for fan-trap-free Text-to-SQL.

46
awslabs/
hcls-agent-skills

Agent skills for healthcare and life sciences: genomics, imaging, claims, drug discovery, and more. Works with Amazon Quick, Kiro, Amazon AgentCore, AWS Strands SDK, Claude Code, Codex, and any Agent Skills-compatible platform.

32

AIPOCH Open-Science is an open-source, local-first, model-agnostic AI research workbench for macOS, Windows, and Linux, with scientific agents, Python/R notebooks, data connectors, and reproducible provenance.

4k
OneInterface/
stormy-cookbook

Open-source cookbook for the Stormy Social Data API and MCP server (Model Context Protocol) — one REST API for the TikTok API, YouTube API, Instagram API, LinkedIn API, X (Twitter) API and Reddit API. Search creators, resolve profiles, read posts and find verified emails from Claude, Cursor, Codex, ChatGPT or curl. One key, no scrapers.

46