Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

Selene is a desktop app that runs AI agents on your machine. Connect them to your WhatsApp, Telegram, Slack, or Discord. Write code, generate images, build personal assistants. All from one place. Your data stays on your device.

Nimbalyst - The open-source visual workspace for Claude Code, Codex, and OpenCode. Run multiple coding agents in parallel, edit their work visually in markdown, mockups, and diagrams, and track tasks. Free, MIT-licensed desktop app for macOS, Windows, Linux, with mobile companion for iOS and Android.

ToolHive is an application that allows you to install, manage and run MCP servers and connect them to AI agents

The Runtime Where AI Agents Build, Ship, and Evolve. Pulse Editor is a modular, cross-platform, AI-powered productivity platform with federated app collaboration and extensible workflows.

Always up-to-date open-source mirror of Claude Code (currently v2.1.152). Run from source with Claude subscription/API, ChatGPT subscription (GPT-5.5 / GPT-5.4), OpenAI-compatible providers, or local Ollama. 18 deep-dive architecture articles included. For educational and reference purposes only.

Enterprise AI Platform with guardrails, MCP registry, gateway & orchestrator

Open-source, desktop-grade AI agent that gets real work done — data analysis, slides, docs, video & web research. Built on OpenClaw; runs tools on your real desktop and takes commands from your phone via WeChat, Feishu, DingTalk & Telegram.

Build agentic systems. Run them with confidence. Orchestrate agents, automate business processes, inspect every execution, and keep humans in control. Deploy Heym on your own infrastructure.

Chat2DB is a free, cross-platform, local-first database client and SQL workspace for developers, DBAs, analysts, and data teams. Connect to 40+ databases, manage data, edit and run SQL, and use your own AI model to generate, explain, and optimize queries. Available on desktop, web, Docker, and CLI, with MCP support.

The Swiss Army Knife of Offline AI. Chat, see, speak, and generate images on your phone or Mac — GGUF LLMs, vision, Whisper speech-to-text, Stable Diffusion, tool calling, and local-network servers. Runs on your CPU, GPU, or NPU. No account, no API key, zero data leaves your device.

The agent IDE that builds itself

Eigent: The Open Source Cowork Desktop - Local and Free Alternative to Claude Cowork and Codex

Edit DOCX/XLSX/PPTX in your browser — client-side, no server, works offline (OnlyOffice + WebAssembly)

Comate is a desktop AI workspace that brings Claude Code into a polished, native app experience. Organize multiple projects in folder-backed workspaces, chat with AI through streaming sessions, explore files, and manage tasks — all in one place.

Open-source HCM system for managing HR processes with AI agents. Full data ownership, MCP/A2A-native, no vendor lock-in.

Open-source desktop AI agent workspace with one-click Claude Code, Codex, OpenClaw, Hermes Agent setup and custom LLM model routing.

Open-source multi-agent AI desktop client — build and command your AI agent team through conversation. A commander LLM dispatches sub-agents in parallel or in series; agents self-evolve via reflection and skill crystallization. Local-first, BYO LLM keys (Claude · OpenAI · Gemini · DeepSeek · Kimi · GLM · Qwen). macOS / Windows / Linux.