AIPOCH Open-Science is an open-source, local-first, model-agnostic AI research workbench for macOS, Windows, and Linux, with scientific agents, Python/R notebooks, data connectors, and reproducible provenance.

Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

OpenHuman is an open source personal AI for Mac, Windows and Linux — local-first memory, agent orchestration, and deep research.

The simplest, fastest repository for training/finetuning medium-sized GPTs.

Powerful AI Client

A collection of notes on Data Science

Mazzap, part of the Mazzstack: essentials for the Singularity Slowlife

User-friendly AI Interface (Supports Ollama, OpenAI API, ...)

A native macOS AI chat app powered by MLX. 100% local inference on Apple Silicon, no cloud required. Built with ShipSwift.

Daily Leetcode masterclass with Claude code DSA mentor

The unified workspace where open-source models get things done for you.

A mechanism for discovering Agent Skills using the .well-known URI path prefix as specified in RFC 8615 for discovering Agent Skills.

Atari Lynx emulator, debugger, and embedded MCP server for macOS, Windows, Linux, BSD and RetroArch.

Eigent: The Open Source Cowork Desktop - Local and Free Alternative to Claude Cowork and Codex

A multi-model AI agent desktop client — connect any AI provider, extend with MCP & skills, control from your phone. Built with Electron + Next.js.

Open-source AI coworker, with memory

Multi-Agent works on native GUI desktop. Supports skills and IM channel, build-in a IDE for light development. Built on the shared piscis-engine kernel.

AI assistant built with Streamlit, NVIDIA NIM (LLaMa 3.3:70B) / Ollama, and Model Control Protocol (MCP).

An offline-first scientific writing workspace powered by Claude. LaTeX + Python + 100+ scientific skills all running locally.

From-scratch, byte-matching decompilation of Super Mario 64 DS (sm64ds decomp) into C, with a live progress atlas and matching tools.

Formerly Better Chatbot. Navigator is an open-source AI workspace for agents, MCP and workflow automation.

Sega Master System / Game Gear / SG-1000 emulator, debugger and embedded MCP server for macOS, Windows, Linux, BSD and RetroArch.

A fully functional AI Agent desktop client that supports Webui access and can be creatively customized and expanded!

eShopLite is a set of reference .NET applications implementing an eCommerce site with features like Semantic Search, MCP, Reasoning models and more.