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10 repos for running · Other · ResearchClear

Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

1.1k
tercumantanumut/
selene

Selene is a desktop app that runs AI agents on your machine. Connect them to your WhatsApp, Telegram, Slack, or Discord. Write code, generate images, build personal assistants. All from one place. Your data stays on your device.

168
wuwangzhang1216/
claude-code-source-all-in-one

Always up-to-date open-source mirror of Claude Code (currently v2.1.152). Run from source with Claude subscription/API, ChatGPT subscription (GPT-5.5 / GPT-5.4), OpenAI-compatible providers, or local Ollama. 18 deep-dive architecture articles included. For educational and reference purposes only.

91

Open-source, desktop-grade AI agent that gets real work done — data analysis, slides, docs, video & web research. Built on OpenClaw; runs tools on your real desktop and takes commands from your phone via WeChat, Feishu, DingTalk & Telegram.

6k
Natively-AI-assistant/
natively-cluely-ai-assistant

Natively — Free open-source AI meeting assistant, interview copilot, and note taker. The best alternative to Cluely, Otter, Granola, Final Round AI, Fireflies, and Interview Coder. Real-time transcription, AI meeting notes, lecture recording, local RAG, BYOK, and stealth mode. Runs locally. No subscriptions. No data breaches.

2.5k
signerlabs/
Klee

A native macOS AI chat app powered by MLX. 100% local inference on Apple Silicon, no cloud required. Built with ShipSwift.

1.8k
eigent-ai/
eigent

Eigent: The Open Source Cowork Desktop - Local and Free Alternative to Claude Cowork and Codex

15k
ai-dvps/
comate

Comate is a desktop AI workspace that brings Claude Code into a polished, native app experience. Organize multiple projects in folder-backed workspaces, chat with AI through streaming sessions, explore files, and manage tasks — all in one place.

93
freestylefly/
wesight

Open-source desktop AI agent workspace with one-click Claude Code, Codex, OpenClaw, Hermes Agent setup and custom LLM model routing.

918
Orkas-AI/
Orkas

Open-source multi-agent AI desktop client — build and command your AI agent team through conversation. A commander LLM dispatches sub-agents in parallel or in series; agents self-evolve via reflection and skill crystallization. Local-first, BYO LLM keys (Claude · OpenAI · Gemini · DeepSeek · Kimi · GLM · Qwen). macOS / Windows / Linux.

1.9k