Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.
1.1k

drhelius/GearlynxOther
Atari Lynx emulator, debugger, and embedded MCP server for macOS, Windows, Linux, BSD and RetroArch.
74
liliu-z/
stashbase
liliu-z/stashbaseOther
Turn your local files into a Wiki for your agents. Open-source and local-first.
605
rowboatlabs/
rowboat
rowboatlabs/rowboatOther
Open-source AI coworker, with memory
18k
speakeasy-api/gramOther
Securely scale AI usage across your organization. A single stack to Connect, Secure, Observe and Distribute agents, MCPs, and Skills within your company.
266
ai-dvps/
comate
ai-dvps/comateOther
Comate is a desktop AI workspace that brings Claude Code into a polished, native app experience. Organize multiple projects in folder-backed workspaces, chat with AI through streaming sessions, explore files, and manage tasks — all in one place.
93
freestylefly/
wesight
freestylefly/wesightOther
Open-source desktop AI agent workspace with one-click Claude Code, Codex, OpenClaw, Hermes Agent setup and custom LLM model routing.
918