Turn your local files into a Wiki for your agents. Open-source and local-first.

AIPOCH Open-Science is an open-source, local-first, model-agnostic AI research workbench for macOS, Windows, and Linux, with scientific agents, Python/R notebooks, data connectors, and reproducible provenance.

Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

OpenHuman is an open source personal AI for Mac, Windows and Linux — local-first memory, agent orchestration, and deep research.

A local-first, encrypted Slack/Discord alternative built for the agentic era. AI agents, such as openclaw, join channels, receive tasks, and coordinate on equal footing with humans — over a serverless P2P mesh.

Open-source multi-agent AI desktop client — build and command your AI agent team through conversation. A commander LLM dispatches sub-agents in parallel or in series; agents self-evolve via reflection and skill crystallization. Local-first, BYO LLM keys (Claude · OpenAI · Gemini · DeepSeek · Kimi · GLM · Qwen). macOS / Windows / Linux.

A fully functional AI Agent desktop client that supports Webui access and can be creatively customized and expanded!

Open-source desktop AI agent workspace with one-click Claude Code, Codex, OpenClaw, Hermes Agent setup and custom LLM model routing.