AIPOCH Open-Science is an open-source, local-first, model-agnostic AI research workbench for macOS, Windows, and Linux, with scientific agents, Python/R notebooks, data connectors, and reproducible provenance.

Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

OpenHuman is an open source personal AI for Mac, Windows and Linux — local-first memory, agent orchestration, and deep research.

A local-first, encrypted Slack/Discord alternative built for the agentic era. AI agents, such as openclaw, join channels, receive tasks, and coordinate on equal footing with humans — over a serverless P2P mesh.

🎨 Best DeepSeek Harness Design Plugin. The open-source Claude Design alternative. 🖥️ Local-first desktop app. 🖼️ Your coding agent becomes the design engine: prototypes, landing pages, dashboards, slides, images & video — real files, HTML/PDF/PPTX/MP4 export. 🤖 Claude Code / Codex / Cursor / DeepSeek Harness / OpenCode & 20+ CLIs via BYOK.

A reactive data store & sync engine.

Enterprise-grade, local-first Agent Workbench for people and agent teams. A unified multi-engine workspace for Codex Harness, DeepSeek Harness, and OpenCode, with unified plugins and Skills, multi-agent projects and tasks, and editable code, documents, presentations, design, and video.

Open-source multi-agent AI desktop client — build and command your AI agent team through conversation. A commander LLM dispatches sub-agents in parallel or in series; agents self-evolve via reflection and skill crystallization. Local-first, BYO LLM keys (Claude · OpenAI · Gemini · DeepSeek · Kimi · GLM · Qwen). macOS / Windows / Linux.

Chat2DB is a free, cross-platform, local-first database client and SQL workspace for developers, DBAs, analysts, and data teams. Connect to 40+ databases, manage data, edit and run SQL, and use your own AI model to generate, explain, and optimize queries. Available on desktop, web, Docker, and CLI, with MCP support.

Where people and agents build in tune.

A fully functional AI Agent desktop client that supports Webui access and can be creatively customized and expanded!

Open-source desktop AI agent workspace with one-click Claude Code, Codex, OpenClaw, Hermes Agent setup and custom LLM model routing.

Stop letting your work go unnoticed. Meridian keeps an automatic work journal of what you worked on and what you finished, summarised daily, and automatically drafts your project tickets for you.