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Claude Code skills for protein design workflows
This repo packages 24 Claude Code skills for computational protein design tasks. The skills cover the workflow from setup and target selection through design, validation, and QC, so Claude can choose the right path for the job.
Builders who use Claude Code for computational protein design and want reusable workflow skills.
You can run protein design tasks with the right skill sequence instead of rebuilding the workflow each time.
What it does
Skill pack for protein design
Provides 24 Claude Code skills for common protein design tasks and subworkflows.
Workflow coverage
Includes skills for binder design, RFdiffusion, ProteinMPNN, Chai, Boltz, AlphaFold, Foldseek, UniProt, and QC steps.
Shared skill pieces
Uses `skills/_shared` for common instructions and building blocks across the skill set.
Getting started and pipeline docs
Explains setup, tool selection, the standard pipeline, compute setup, and troubleshooting in `docs/`.
Plugin install path
Ships with `.claude-plugin/marketplace.json` and `plugin-manifest.json` for Claude Code plugin installation.
How to get it
- 1Run
/plugin marketplace add adaptyvbio/protein-design-skills /plugin install adaptyv@protein-design-skills
README
24 Claude Code skills for computational protein design
Getting started • Skills • Pipeline
Install
/plugin marketplace add adaptyvbio/protein-design-skills
/plugin install adaptyv@protein-design-skills
Setup (first time)
Skills
Pipeline
Quick start
"Design a binder for PDB 1ALU"
Claude will pick the right skills for the target (for example BoltzGen → Chai → QC, or RFdiffusion → ProteinMPNN → Chai → QC).
Links
Contributing
Creating a new skill
The easiest way to create a new skill is with Claude Code:
/skill skill-creator
This uses Anthropic's skill-creator to guide you through the process.
See CONTRIBUTING.md for detailed guidelines.
License
MIT
References
- biomodals - Modal execution wrappers
- Anthropic Skills - Skills specification
Files in the repo
- .claude-plugin
- .github
- assets
- docs
- skills
- .gitignore
- CHANGELOG.md
- CONTRIBUTING.md
- LICENSE
- plugin-manifest.json
- README.md
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